Radiation Stewardship
Introduction
Welcome to the APSA Quality and Safety committee . This page is intended to help anyone who is interested in Quality Improvement (QI) pertaining to radiation stewardship.
Available toolkit projects are listed below. Many of the approaches described are evidence-based - some are not. These approaches have not been approved by APSA.
Projects
Radiographic Stewardship in Trauma
Unnecessary computed tomography (CT) scanning increases health care costs and places children at increased risk of fatal cancers. The University of Rochester aimed to reduce unnecessary CT imaging in pediatric blunt trauma patients by developing imaging algorithms (guidelines) and retrospectively validating them for efficacy and safety. These were then implemented prospectively as part of a QI project to reduce unnecessary scans.
Protocol:
- Guidelines were created after literature review to reduce unnecessary radiographic studies.
- Institutional buy-in was generated by validating the guidelines retrospectively for efficacy and safety and obtaining feedback from stakeholders.
- Education was provided to staff, including trainees, regarding purpose and usage of the tools.
- Algorithms were then implemented prospectively to guide management for traumatically injured children.
- Periodic chart review was performed to identify imaging practices (outcome measure) and missed injuries (balancing measure).
- Repeated Plan, Do, Study, Act (PDSA) cycles were carried out to improve compliance.
Resources:
- Abstracts: describe retrospective and prospective implementation of imaging algorithms at the University of Rochester. Numbered sequentially which corresponds to their chronologic creation. We would recommend viewing them in order.
- URMC ABSTRACT 1 Retrospective validation - Imaging Gently – Validation of Imaging Algorithms to Reduce Radiation Exposure for Pediatric Trauma Patients
- URMC ABSTRACT 2 Prospective Short Term - Imaging Gently – Computed Tomography Reduction in Pediatric Trauma Patients
- URMC ABSTRACT 3 Prospective Long Term - Sustaining the Gains - Further Reductions in Unnecessary Computed Tomography Scans in Pediatric Trauma Patients
- URMC ABSTRACT 4 Prospective LongER Term - Sustaining the Gains - Further Reductions in Unnecessary Computed Tomography Scans in Pediatric Trauma Patients
- Data collection form: sample form used at the University of Rochester to denote what imaging was performed and what was indicated for each pediatric trauma patient. This allows us to track our data over time.
- Imaging guidelines: algorithms used for the head, cervical spine, chest, abdomen and pelvis used at the University of Rochester. Both updated and older guidelines are included.
- URMC Pediatric Blunt Head Trauma Imaging Algorithm UTD (2022)
- URMC Pediatric Blunt Head Trauma Algorithm OLDER GUIDELINE
- URMC Pediatric Blunt Cervical Spine Trauma Management Algorithm UTD (2022)
- URMC Pediatric Blunt Cervical Spine Trauma Management Algorithm OLDER GUIDELINE
- URMC Pediatric Blunt Thoracic Trauma Imaging Algorithm UTD (2022)
- URMC Pediatric Blunt Thoracic Trauma Imaging Algorithm OLDER GUIDELINE
- URMC Pediatric Blunt Abdominal Trauma Imaging Algorithm UTD (2022)
- URMC Blunt Abdominal Trauma Imaging Algorithm OLDER GUIDELINE
- IRB Protocol: sample IRB protocol accepted by the University of Rochester IRB.
- Posters: presented describing retrospective and prospective implementation of imaging algorithms at the University of Rochester.
- Presentations: sample presentations given to stakeholders (in this case, surgical residents) to provide an update and get buy-in for the imaging reduction QI initiative. The presentations are displayed sequentially corresponding to their creation chronologically.
Stakeholders: pediatric blunt trauma victims, pediatric trauma team, pediatric ED, pediatric radiology, orthopedic surgery, neurosurgery, PICU, hospital leadership, malpractice insurer
Challenges and Solutions:
- Challenge #1: Changing the culture in the ED from pan-scanning to selectively scanning based on mechanism, signs, symptoms, and other data (lab and radiographic).
- Solution #1: Meeting with all stakeholders and addressing their concerns. Meeting with peds ED and surgical residents and explaining the rationale for the change in practice. The attached PowerPoint presentations were used to educate the residents and peds ED staff about the project. We also used this time to listen to and address their concerns, which likely improved buy-in.
- Challenge #2: Getting providers easy access to the guidelines.
- Solution #2: Widespread dissemination in the ED and to surgical residents. Creating an electronic web based calculator.
- Challenge #3: Building in a process measure to determine if the guidelines are being used.
- Solution #3: A web calculator was built that tracks when the online version of the guideline is used. We are looking into building a pediatric trauma imaging order set with a prompt and link to the guidelines before ordering CT scans.
- Challenge #4: Improving adherence to the cervical spine algorithm. Initial reductions in unnecessary CT imaging were likely due to compliance with chest imaging.
- Solution #4: In order to improve compliance further, we placed emphasis on adherence to the cervical spine guideline in July 2019 and started giving direct provider feedback for nonadherance in early 2020. Based on the run chart below, direct provider feedback seems to have caused a further reduction in the number of CT obtained that are not indicated by our guidelines.
Links to published data (used to develop the protocol): manuscripts are in preparation, please refer to the abstracts (under Resources) for presented work.
- For articles relevant to pediatric trauma imaging, please refer to: [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]
Submitted by: Derek Wakeman, MD
For additional information on guidelines pertaining to imaging, please refer to:
Intraoperative Radiation Reduction
Pediatric central venous lines (CVL) are frequently placed using fluoroscopy in the operating room. Few surgeons receive proper training on radiation protection, likely resulting in unnecessary radiation exposure to patients and staff. In order to minimize radiation, during and after CVL placement, Hassenfeld Children’s Hospital at NYU Langone instituted a strict fluoroscopic dose reduction intervention consisting of: (a) radiation safety training for staff; (b) implementation of a mandatory radiation safety time-out prior to C-arm use; and (c) limitation of postprocedural radiographs for asymptomatic patients. This initiative reduced the estimated radiation to the patient (as measured by DAP) almost fivefold. This decrease was corroborated by a nearly fourfold decrease in total radiation time.
Protocol:
- A safety briefing to OR staff before each case which included information on the direction of radiation beams, dose reduction techniques, and the proper way to shield the patient and staff in the OR case
- A time-out was performed before every procedure that required the use of a fluoroscopic C-arm
- No post-operative CXR (final fluoroscopy image is saved to PACS)
Resources:
- NYU Langone Health - Pediatric Intraop Radiation Reduction Time-out
- NYU Langone Health - PPT - Simple PreOp Safety Interventions Significantly Lower Radiation Doses During CVL Placement in Children
- NYU Langone Health - APSA 2018 Visual Abstract - Impact of Pre-Operative Time-Out on Radiation Exposure from Fluoroscopy
Stakeholders: pediatric surgery, pediatric radiology
Challenges and Solutions: Consistent adherence to the protocol was enhanced by use of the time-out protocol, using principles of structured surgical checklists, which have been shown to be low-cost, highly effective tools for improving patient outcomes and reducing complications.
Links to published data (used to develop the protocol):[25]
Submitted by: Sandra Tomita, MD
Decreasing CT Use in Appendicitis Patients
St. Joseph’s Children’s Hospital in Tampa developed a quality initiative focused on decreasing unnecessary CT scans while determining a diagnosis of appendicitis through assessment with the pediatric appendicitis score (PAS) and use of radiation-free diagnostic imaging. This initiative resulted from a review of the institution’s NSQIP Pediatric Semiannual Report that revealed a higher than average CT utilization and high negative appendectomy rate to CT utilization. A thorough literature review of best practices, current protocols for the diagnosis of appendicitis in ER, and imaging modalities used to diagnose cases in 2017, was undertaken. Moreover, surgeons reached out to other institutions to inquire about protocols being utilized. Thereafter, a multidisciplinary team was created which included emergency room physicians, radiologists and pediatric surgeons to create an algorithm for the diagnosis and treatment of appendicitis. The algorithm was presented at appropriate committees and was subsequently adopted as a best practice medical standard by the Health System.
Protocol:
Resources:
Stakeholders:
- Medical Director of Pediatric Surgery, Grant Geissler, MD
- Pediatric Emergency Medicine Physician, Worth Barbour, MD
- Pediatric Radiologist, Timothy Bonsack, MD
- Pediatric Hospitalist, Christina Canody, MD
- Pediatric Surgical Program Coordinator, Kirsten Yancy, RN
- Evidence Based Medicine Members: Paul Lewis, MD and Pamela Morell, RN
Challenges and Solutions:
Challenges:
- Documentation of the PAS score by the ER physician in the EMR
- Education to all ER physicians
- Education to community ER physicians about best practice for the diagnosis of appendicitis
Solutions:
- Working with the IT department to embed the PAS score in EMR documentation, providing education to ER physicians on consistently documenting the PAS score
- Working on presenting the insitutional best practice medical standard to each Health System Hospital
- Looking at opportunities for community education- work still in progress
Links to published data (used to develop the protocol): [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40]
Submitted by: Grant Geissler, MD
Additonal Implementers: Kirsten Yancy, RN, BSN, CPN
In order to optimize the utility of ultrasound (US) at Children’s Healthcare of Atlanta (CHOA), a QI initiative was implemented consisting of the development and validation of a right lower quadrant ultrasound template that reported secondary signs (SS) and categorized diagnostic confidence and disease severity for acute appendicitis. Concurrently, the patients undergoing CT A/P and those being admitted for observation were also being tracked. The outcomes of interest included: high compliance rates of utilizing the standardized US report, lower CT A/P use, fewer admissions for observation, duration of symptoms was associated with more SS, and equivocal US that included hyperemia, fluid collection, or appendicolith had 96% specificity and 88% accuracy.
Protocol:
Resources:
- CHOA Poster - Improving Ultrasound For Appendicitis Through Standardized Reporting Of Secondary Signs
- CHOA PPT - Do Secondary Signs Matter in Ultrasound Reporting for Suspected Appendicitis in Children?
Stakeholders: emergency department (ED), radiology, surgery, QI team
Challenges and Solutions: This QI initiative led to high compliance rates of utilizing the standardized US report and resulted in lower CT A/P use and fewer admissions for observation. We found that our colleagues in radiology were amenable to using the US template and had relatively easy/rapid implementation. We also found that both the ED and Surgery faculty/staff thought that the templated reports provided more detail and facilitated improved decision making.
Links to published data (used to develop the protocol): [41][42][43]
Submitted by: Mehul Raval, MD, MS
Additional implementers: Kurt Heiss, MD
Texas Children’s Hospital (TCH) also developed and validated an ultrasound scoring system for children with suspected acute appendicitis. The goal of standardizing the reporting of an appendiceal US by means of a structured template system was to risk-stratify patients with suspected pediatric appendicitis, and measure the effect of this scoring system on US diagnostic performance measures, follow-up CT exam rates and negative appendectomy rates.
Protocol:
Resources:
Stakeholders: emergency department (ED), radiology, surgery
Challenges and Solutions: The use of a risk stratification scoring system and structured template for reporting US exam results for suspected pediatric appendicitis improved communication of appendicitis likelihood to all the teams involved in the care of the patient. It did not seem to affect ED process measures such as total ED length of stay. Further analysis of data generated from this study allowed identification of factors that further discriminate between simple and perforated appendicitis based on the US.
Links to published data (used to develop the protocol): [44][45][46][47]
Submitted by: Monica Lopez, MD
Texas Children’s Hospital (TCH) also adopted Standing Delegation Orders (SDO) for US based on PAS scores assessed by ED triage nursing staff in order to minimize LOS in the ED phase of care. A surgical hospitalist pilot was launched concurrently with the goal of facilitating prompt surgical evaluations in the ED.
Protocol:
- TCH PPT - Update on EC Interventions for Appendicitis Evaluations (Triage Nursing SDO)
- The slide deck above summarizes the pathway and the decision support that was built to integrate the PAS score into the US radiology orders. This project was part of a multifaceted intervention addressing LOS in all phases of care, as a shared savings program for appendectomy was piloted.
Resources:
- TCH Evidence-Based Outcomes Center: Acute Appendicitis/Appendectomy Management Algorithm
- TCH Evidence-Based Outcomes Center: Acute Appendicitis/Appendectomy Evidence-Based Guideline
Stakeholders: emergency department (ED), surgery, radiology, anesthesia, nursing, perioperative services, financial services, hospital administration
Submitted by: Monica Lopez, MD
At Nemours/Alfred I. DuPont Hospital for Children, a retrospective review was performed to identify patient characteristics associated with non-diagnostic ultrasounds in children with suspected appendicitis. Patients with a moderate PAS were likely to have non-diagnostic ultrasound, whereas, patients with high PAS were ikely to have appendicitis diagnosed on ultrasound. A hybrid approach to imaging patients with suspected appendicitis based on PAS was developed in which low PAS requires no imaging studies, moderate PAS get an MRI vs. no imaging, according to index of suspicion, and high PAS undergo an ultrasound. The current appendicitis imaging order (for MRI or ultrasound) has an embbeded PAS calculator, and requires input of the PAS.
Protocol:
Resources:
Stakeholders: surgery, radiology, ED
Challenges and Solutions:
- ED hesitant to discharge kids without any imaging, even in low/moderate PAS groups.
- Institutions must have experience and easy access to MRI 24x7.
Submitted by: Loren Berman, MD
In the evaluation of appendicitis, imaging is often obtained to confirm the diagnosis. While US is often considered a first-line imaging modality, there may be reasons, such as equivocal imaging or issues related to availability/reliability, that may prompt cross-sectional imaging (i.e., CT or MRI). Additionally, although US is often cited to have high diagnostic performance for appendicitis, recent studies have questioned its true sensitivity in clinical practice. At Penn State Children’s Hospital, the desire to avoid the potential radiation associated with CT scan, and the ready availability of MRI (Children’s Hospital within a General Health System sharing MRI resources) led to an investigation of MRI in the diagnostic evaluation of pediatric appendicitis. Based on the diagnostic accuracy and reliability of MRI in diagnosing or excluding appendicitis, characterizing alternative pathology, and facilitating ED disposition, as well as acceptable clinical time-related parameters (e.g., time from request to scan, imaging duration, time from request to interpretation), an appendicitis pathway was implemented and evaluated utilizing MRI as the primary imaging modality.
Key Results:
● 30 month institutional experience (n=510), 98% of patients ≥ 5 years old
● No IV/oral contrast MRI protocol
● Diagnostic Performance
o Sensitivity: 96.8%
o Specificity: 97.4%
o Positive Predictive Value: 92.4%
o Negative Predictive Value: 98.9%
● Time Parameters (median):
o Time from request to scan: 71 minutes
o Imaging duration: 11 minutes
o Time from last sequence to interpretation: 31 minutes
o Time from request to interpretation: 2 hrs
Protocol:
Resources:
- PennState Health Hershey - MRI Appendicitis Plane/Sequence Details
- PennState Health Hershey - MRI Appendicitis Pathway Pre-Covid
Stakeholders: pediatric surgery, pediatric radiology, pediatric ED, ultrasound and MRI technologists
Challenges and Solutions: The program required buy-in from all pediatric surgeons, ED physicians, radiologists and technologists. Initially, coordination between the ED and technologists for scheduling MRI times, and interpretation was challenging, but improved as the MRI sequences were refined, timely MRI requests and scanning time became more predictable, and familiarity with the protocol grew. Additionally, skill in interpretation of appendicitis on MRI had to be developed and refined.
Links to published data (used to develop the protocol): [33][48][49][50][51][52][53][54][55][56]
Submitted by: Afif Kulaylat, MD, MSc
Recent Research
For recent research pertaining to radiation stewardship initiatives, please refer to the references
References
- Drexel S, Azarow K, Jafri MA. Abdominal Trauma Evaluation for the Pediatric Surgeon. Surg Clin North Am. 2017;97(1):59-74. [PMID:27894432]
- Arbra CA, Vogel AM, Plumblee L, et al. External validation of a five-variable clinical prediction rule for identifying children at very low risk for intra-abdominal injury after blunt abdominal trauma. J Trauma Acute Care Surg. 2018;85(1):71-77. [PMID:29659473]
- Streck CJ, Vogel AM, Zhang J, et al. Identifying Children at Very Low Risk for Blunt Intra-Abdominal Injury in Whom CT of the Abdomen Can Be Avoided Safely. J Am Coll Surg. 2017;224(4):449-458.e3. [PMID:28130170]
- Calder BW, Vogel AM, Zhang J, et al. Focused assessment with sonography for trauma in children after blunt abdominal trauma: A multi-institutional analysis. J Trauma Acute Care Surg. 2017;83(2):218-224. [PMID:28590347]
- Karam O, Sanchez O, Chardot C, et al. Blunt abdominal trauma in children: a score to predict the absence of organ injury. J Pediatr. 2009;154(6):912-7. [PMID:19230903]
- Holscher CM, Faulk LW, Moore EE, et al. Chest computed tomography imaging for blunt pediatric trauma: not worth the radiation risk. J Surg Res. 2013;184(1):352-7. [PMID:23746760]
- Hershkovitz Y, Zoarets I, Stepansky A, et al. Computed tomography is not justified in every pediatric blunt trauma patient with a suspicious mechanism of injury. Am J Emerg Med. 2014;32(7):697-9. [PMID:24856745]
- Mavros MN, Kaafarani HM, Mejaddam AY, et al. Additional Imaging in Alert Trauma Patients with Cervical Spine Tenderness and a Negative Computed Tomographic Scan: Is it Needed? World J Surg. 2015;39(11):2685-90. [PMID:26239776]
- Fenton SJ, Hansen KW, Meyers RL, et al. CT scan and the pediatric trauma patient--are we overdoing it? J Pediatr Surg. 2004;39(12):1877-81. [PMID:15616956]
- Yanchar NL, Woo K, Brennan M, et al. Chest x-ray as a screening tool for blunt thoracic trauma in children. J Trauma Acute Care Surg. 2013;75(4):613-9. [PMID:24064874]
- Tan KK, Bang SL, Vijayan A, et al. Hepatic enzymes have a role in the diagnosis of hepatic injury after blunt abdominal trauma. Injury. 2009;40(9):978-83. [PMID:19535055]
- Bruhn PJ, Østerballe L, Hillingsø J, et al. Posttraumatic levels of liver enzymes can reduce the need for CT in children: a retrospective cohort study. Scand J Trauma Resusc Emerg Med. 2016;24(1):104. [PMID:27561373]
- Scaife ER, Rollins MD. Managing radiation risk in the evaluation of the pediatric trauma patient. Semin Pediatr Surg. 2010;19(4):252-6. [PMID:20889080]
- Ide K, Uematsu S, Tetsuhara K, et al. External Validation of the PECARN Head Trauma Prediction Rules in Japan. Acad Emerg Med. 2017;24(3):308-314. [PMID:27862642]
- Sola JE, Cheung MC, Yang R, et al. Pediatric FAST and elevated liver transaminases: An effective screening tool in blunt abdominal trauma. J Surg Res. 2009;157(1):103-7. [PMID:19592033]
- Holmes JF, Mao A, Awasthi S, et al. Validation of a prediction rule for the identification of children with intra-abdominal injuries after blunt torso trauma. Ann Emerg Med. 2009;54(4):528-33. [PMID:19250706]
- Cook SH, Fielding JR, Phillips JD. Repeat abdominal computed tomography scans after pediatric blunt abdominal trauma: missed injuries, extra costs, and unnecessary radiation exposure. J Pediatr Surg. 2010;45(10):2019-24. [PMID:20920722]
- Hom J. The risk of intra-abdominal injuries in pediatric patients with stable blunt abdominal trauma and negative abdominal computed tomography. Acad Emerg Med. 2010;17(5):469-75. [PMID:20536798]
- Stephens CQ, Boulos MC, Connelly CR, et al. Limiting thoracic CT: a rule for use during initial pediatric trauma evaluation. J Pediatr Surg. 2017;52(12):2031-2037. [PMID:28927984]
- Karaduman D, Sarioglu-Buke A, Kilic I, et al. The role of elevated liver transaminase levels in children with blunt abdominal trauma. Injury. 2003;34(4):249-52. [PMID:12667774]
- Retzlaff T, Hirsch W, Till H, et al. Is sonography reliable for the diagnosis of pediatric blunt abdominal trauma? J Pediatr Surg. 2010;45(5):912-5. [PMID:20438925]
- Streck CJ, Jewett BM, Wahlquist AH, et al. Evaluation for intra-abdominal injury in children after blunt torso trauma: can we reduce unnecessary abdominal computed tomography by utilizing a clinical prediction model? J Trauma Acute Care Surg. 2012;73(2):371-6; discussion 376. [PMID:22846942]
- Markel TA, Kumar R, Koontz NA, et al. The utility of computed tomography as a screening tool for the evaluation of pediatric blunt chest trauma. J Trauma. 2009;67(1):23-8. [PMID:19590303]
- Acker SN, Stewart CL, Roosevelt GE, et al. When is it safe to forgo abdominal CT in blunt-injured children? Surgery. 2015;158(2):408-12. [PMID:25999252]
- Choi BH, Yaya K, Prabhu V, et al. Simple preoperative radiation safety interventions significantly lower radiation doses during central venous line placement in children. J Pediatr Surg. 2019;54(1):170-173. [PMID:30415958]
- Samuel M. Pediatric appendicitis score. J Pediatr Surg. 2002;37(6):877-81. [PMID:12037754]
- Blitman NM, Anwar M, Brady KB, et al. Value of Focused Appendicitis Ultrasound and Alvarado Score in Predicting Appendicitis in Children: Can We Reduce the Use of CT? AJR Am J Roentgenol. 2015;204(6):W707-12. [PMID:26001260]
- Hall EJ, Brenner DJ. Cancer risks from diagnostic radiology. Br J Radiol. 2008;81(965):362-78. [PMID:18440940]
- Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect (Larchmt). 2010;11(1):79-109. [PMID:20163262]
- Bachur RG, Levy JA, Callahan MJ, et al. Effect of Reduction in the Use of Computed Tomography on Clinical Outcomes of Appendicitis. JAMA Pediatr. 2015;169(8):755-60. [PMID:26098076]
- Kotagal M, Richards MK, Flum DR, et al. Use and accuracy of diagnostic imaging in the evaluation of pediatric appendicitis. J Pediatr Surg. 2015;50(4):642-6. [PMID:25840079]
- Brenner D, Elliston C, Hall E, et al. Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR Am J Roentgenol. 2001;176(2):289-96. [PMID:11159059]
- Aspelund G, Fingeret A, Gross E, et al. Ultrasonography/MRI versus CT for diagnosing appendicitis. Pediatrics. 2014;133(4):586-93. [PMID:24590746]
- Goldman RD, Carter S, Stephens D, et al. Prospective validation of the pediatric appendicitis score. J Pediatr. 2008;153(2):278-82. [PMID:18534219]
- Herliczek TW, Swenson DW, Mayo-Smith WW. Utility of MRI after inconclusive ultrasound in pediatric patients with suspected appendicitis: retrospective review of 60 consecutive patients. AJR Am J Roentgenol. 2013;200(5):969-73. [PMID:23617477]
- Neff LP, Ladd MR, Becher RD, et al. Computerized tomography utilization in children with appendicitis-differences in referring and children's hospitals. Am Surg. 2011;77(8):1061-5. [PMID:21944524]
- Fahimi J, Herring A, Harries A, et al. Computed tomography use among children presenting to emergency departments with abdominal pain. Pediatrics. 2012;130(5):e1069-75. [PMID:23045569]
- Humes, D.J., Simpson, J. (2012). Clinical Presentation of Acute Appendicitis: Clinical Signs—Laboratory Findings—Clinical Scores, Alvarado Score and Derivate Scores. In: KEYZER, C., Gevenois, P. (eds) Imaging of Acute Appendicitis in Adults and Children. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_211.
- Saucier A, Huang EY, Emeremni CA, et al. Prospective evaluation of a clinical pathway for suspected appendicitis. Pediatrics. 2014;133(1):e88-95. [PMID:24379237]
- Foundation, A. B. I. M. (2015, February 26). ACS - CT in evaluation of appendicitis in children: Choosing wisely. Choosing Wisely | Promoting conversations between providers and patients. Retrieved April 21, 2022, from http://www.choosingwisely.org/clinician-lists/american-college-surgeons-computed-tomography-to-evaluate-appendicitis-in-children.
- Partain KN, Patel A, Travers C, et al. Secondary signs may improve the diagnostic accuracy of equivocal ultrasounds for suspected appendicitis in children. J Pediatr Surg. 2016;51(10):1655-60. [PMID:27039121]
- Partain KN, Patel AU, Travers C, et al. Association of Duration of Symptoms and Secondary Signs in Ultrasound for Pediatric Appendicitis. Am Surg. 2016;82(9):e266-8. [PMID:27670544]
- Partain KN, Patel AU, Travers C, et al. Improving ultrasound for appendicitis through standardized reporting of secondary signs. J Pediatr Surg. 2017;52(8):1273-1279. [PMID:27939802]
- Fallon SC, Orth RC, Guillerman RP, et al. Development and validation of an ultrasound scoring system for children with suspected acute appendicitis. Pediatr Radiol. 2015;45(13):1945-52. [PMID:26280638]
- Abbas PI, Zamora IJ, Elder SC, et al. How Long Does it Take to Diagnose Appendicitis? Time Point Process Mapping in the Emergency Department. Pediatr Emerg Care. 2018;34(6):381-384. [PMID:29851913]
- Telesmanich ME, Orth RC, Zhang W, et al. Searching for certainty: findings predictive of appendicitis in equivocal ultrasound exams. Pediatr Radiol. 2016;46(11):1539-45. [PMID:27282824]
- Mangona KLM, Guillerman RP, Mangona VS, et al. Diagnostic Performance of Ultrasonography for Pediatric Appendicitis: A Night and Day Difference? Acad Radiol. 2017;24(12):1616-1620. [PMID:28826614]
- Kulaylat AN, Moore MM, Engbrecht BW, et al. An implemented MRI program to eliminate radiation from the evaluation of pediatric appendicitis. J Pediatr Surg. 2015;50(8):1359-63. [PMID:25783291]
- Moore MM, Brian JM, Methratta ST, et al. MRI for clinically suspected pediatric appendicitis: case interpretation. Pediatr Radiol. 2014;44(5):605-12. [PMID:24442340]
- Moore MM, Gustas CN, Choudhary AK, et al. MRI for clinically suspected pediatric appendicitis: an implemented program. Pediatr Radiol. 2012;42(9):1056-63. [PMID:22677910]
- Moore MM, Kulaylat AN, Brian JM, et al. Alternative diagnoses at paediatric appendicitis MRI. Clin Radiol. 2015;70(8):881-9. [PMID:26072983]
- Moore MM, Kulaylat AN, Hollenbeak CS, et al. Magnetic resonance imaging in pediatric appendicitis: a systematic review. Pediatr Radiol. 2016;46(6):928-39. [PMID:27229509]
- Mushtaq R, Desoky SM, Morello F, et al. First-Line Diagnostic Evaluation with MRI of Children Suspected of Having Acute Appendicitis. Radiology. 2019;291(1):170-177. [PMID:30747595]
- Dillman JR, Trout AT. MRI for First-Line Evaluation of Children Suspected of Having Acute Appendicitis. Radiology. 2019;291(1):178-179. [PMID:30776248]
- Desoky S, Udayasankar UK. Unenhanced MRI for Abdominal Pain in the Pediatric Emergency Department: Point-Safe and Comprehensive Assessment While Reducing Delay in Care. AJR Am J Roentgenol. 2021;216(4):874-875. [PMID:32876486]
- Brian JM, Moore MM. Unenhanced MRI for Abdominal Pain in the Pediatric Emergency Department: Counterpoint-Choice Should Consider Access, Patient, and Cost. AJR Am J Roentgenol. 2021;216(4):876-877. [PMID:32876483]

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